Author(s): Khalid Eqbal, Md. Anzar Alam and Mohd Aleemuddin Quamri

Abstract:
Diabetes mellitus (DM) is a metabolic disorder with multiple etiologies, characterized by chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action or both. It may leads to many acute and chronic complications. Such type of chronic complications is mainly due to the result of longstanding damage to blood vessels. These complications are mainly classified as microvascular due to basement membrane thickening or macrovascular due to accelerated atherosclerosis. The major micovascular complications are diabetic retinopathy, diabetic neuropathy and diabetic nephropathy. Complications of diabetic are totally due to poor glycemic control. Unani Medicine is the thrusting area of research to control or reduced the complications of diabetes. Several Unani drugs (mufrad and murakkab) exhibits anti-diabetic activity, nootropic ativity, antioxidant activity, immunomodulator activity such as Gilo, Saadkofi, Jatamani, Berge Sena, Darhald, Post Kachnal, Aqerqarha, Azaraqui, Beesh, Balchhar, Tukhme Khurfa, Dammul Akhwain, Kabab Chini, Darchini, Tukhm Methi, Gurmar Booti, Asgand etc., and some compounds are Safoof-e-Ziabetus, Qurs-e-Ziabetus, Qurs-e-Gulnar, Qurs-e-Tabsheer, Habb-e-Asab, Habb-e-Azaraqui, Kushta Qalai etc. Aim of this case series study is explore the benefits of Polyherbal Unani Formulation on their scientific parameters to reduce the burden of diabetes.

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